Apr 06, 2021
What is Oral CMF:
This is a chemotherapy treatment with combination of three drugs used
to treat breast cancer.
Cyclophosphamide is given as oral tablets, and both methotrexate and fluorouracil will be given through infusion in the veins.
How oral CMF Works:
o Cyclophosphamide is a type of chemotherapy medicine called an alkylating agent and also called Cytoxan. It stops cancer cells from reproducing.
o Both Methotrexate and Fluorouracil are related to another type of chemotherapy medicine called antimetabolites. They stop DNA synthesis in cancer cells thus preventing cancer cells growth and division.
Who Gets oral CMF:
How is oral CMF Given:
supplements and over-the-counter medicines, to make sure they won’t interfere with your CMF treatment.
What are the side effects from Oral CMF treatment:
It is important to remember that different medicines have different side effects for different people.
You may not have every side effect related to each medicine of the combination therapy.
Common side-effects of CMF include:
Your doctor will be monitoring your blood counts weekly in the first two weeks of each cycle.
It is very important to follow your doctor’s instructions regarding taking the antinausea medications, to avoid this side-effect and its complications.
Less common but more serious side effects include:
This can sometimes occur with fluorouracil. Call your doctor right away in case you had chest pain, tightness at the center of your chest, palpitations or bounding chest.
Talk to your doctor, pharmacist or nurse about all your side effects so that they can help you
manage them. For managing a specific side effect, please watch our symptom specific video.
Virginia, United States
I am a HER2 negative ER positive stage IV breast cancer patient. Last year, wonderful doctors here suggested me to test for PIK3CA mutation (cobas® PIK3CA Mutation Test). It was found positive.
My Newport Beach oncologist put me Piqray + Faslodex combo since nine months. I got test reports two months in a row. THANK GOD, my tumor is stable! Thank you Doctors! I urge members with stage 4 cancer here not to lose hope or give up.
Florida, United States
I had posted last year about my husband who has been diagnosed with stage 3 esophageal cancer. His is an esophageal squamous cell carcinoma type, so there was a consensus among his oncologist at FCS and Oncopower doctors here that Opdivo + Yervoy is the best option I am happy to share an update that he is doing well. His appetite has increased, follows recommended diet and regained some of the weight. We will keep our fingers crossed though!
Pennsylvania, United States
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Iowa , United States
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Western Cape, South Africa
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Floroda United States
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Florida, United States
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New York, United States
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California, United States
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